| Titles |
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English :
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Effect of folic acid on semen quality and biochemical parameters of rabbits
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Arabic :
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تأثر اضافة حامض الفوليك على جودة السائل المنوى و المعايير البيوكيميائية لذكور الارانب
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| Abstract |
The objective of this study was to determine the effects of different levels of folic acid supplementation on sperm characteristics, seminal plasma lipid peroxidation and enzyme activities of mature rabbits.
Twenty-four male New Zealand White rabbits(7 months old) were divided into four equal groups. The first group was served as control, while groups 2, 3, and 4 were orally treated with low (40 μg/kg of body weight), medium (80 μg/kg of body weight) and high doses (160 μg/kg of body weight), respectively of folic acid every other day for 12 weeks. Ejaculate volume (EV), sperm concentration, total sperm output, sperm motility (0/0), total motile sperm per ejaculate, packed sperm volume, total functional sperm 'action (TFSF) compared to the control. Normal sperms and initial fructose were found to be significantly (P < 0.05) increased due treatments with low or medium doses of folic acid compared to the control.
However, reaction time and dead sperm were significantly (P<0.05) decreased. On the other hand, high dose of folic acid did not show any significant (P < 0.05) effect on the most of previous semen parameters compared to the control group.
Administration of folic acid increased (P < 0.05) seminal plasma total protein (TP), albumin (Alb), aspartate aminotransferase (AST), alaninal aminotransferase (ALT) and acid phosphatase (AcP). Conversely, seminal plasma urea and glucose were significantly decreased compared to the control. Concentration of thiobarbituric acid-reactive substances (TBARS) was significantly (P < 0.05) reduced in seminal plasma of rabbits treated with all doses of folic acid While, the activities of glutathione S-transferase (GST) and superoxide dismutase (SOD) were significantly increased compared with control. These results showed that treatments with folic acid caused an improvement of some semen characteristics in rabbits especially with low and medium doses without any harmful or negative effects on male fertility.
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| Publication year |
1997
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| Pages |
373-394
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| Availability location |
معهد بحوث الانتاج الحيوانى-شارع نادى الصيد- الدقى- الجيزة
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| Availability number |
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| Organization Name |
Animal Production Research Institute (APRI)
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| City |
الاسكندرية
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| serial title |
Egyptian Poultry Science
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| ISSN |
1110-5623
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| Author(s) from ARC |
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| Agris Categories |
Animal physiology - Reproduction
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AGROVOC
TERMS |
Acid phosphatase.
Albumins.
Aspartate aminotransferase.
Folic acid.
Rabbits.
Semen.
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| Proposed Agrovoc |
semen quality;seminal plasma lipid;enzyme activities;seminal plasma total protein;alaninal aminotransferase;
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| Publication Type |
Journal
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