Titles |
English :
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Genotype and age effects on immunity traits, corticosterone and oxidative status in growing rabbits
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Abstract |
To investigate the effects of genotype and age on native immunity, corticosterone and oxidative status 60 weaned rabbits were used; 30 Native Middle-Egypt rabbits (NMER) and 30 New Zealand White (NZW). Blood samples were collected and analyzed from each rabbit at 45, 60, and 75 d of age. Native immunity were included count and differential count of leukocyte, Serum Bactericidal Activity –SBA, Hemolytic complement Assay–HCA, lysozyme). Oxidative status (Reactive Oxygen Substances–ROS and total Antioxidant Capacity of plasma, TAC) were estimated in plasma. Genotype was an important source of variation (p< 0.01) for leukocytes where NMER was higher than NZW. Effect of age was not significant in Leukocytes. Genotype and age had significant (p<0.05) effect in both of Netruphile and Lymphocyte. Netruphile was increased while lymphocyte decreased at 45 d (after 10 d from weaning). Corticosterone levels at 45 days were higher than at others ages in both breeds. Breed significantly influenced Lysozyme and SBA in native immunity traits. NMER rabbits were characterized by a higher lysozyme, an increased SBA and complement when compared to NZW rabbits at different age. Lysozyme and HCA trends were higher at 45d than at 60 d, whereas the SBA increased with age. Reduced plasma levels of ROS in NMER rabbits at 60 and 75 days of age compared to NZW. TAC and ROS were significantly (p<0.05) affected by age while breed had no significant effect It can be concluded that NMER rabbits were characterized by of native immunity traits (lysozyme, SBA and complement) when compared to NZW rabbits at different ages.
Key words: Middle-Egypt rabbits, genotype, immunity, corticosterone, oxidative status, age
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Publication year |
2012
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Pages |
107-111
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Availability location |
معهد بحوث الانتاج الحيوانى- شار ع نادى الصيد- الدقى - الجيزة
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Availability number |
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Organization Name |
Animal Production Research Institute (APRI)
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City |
شرم الشيخ
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serial title |
10 th World Rabbit Congress
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Author(s) from ARC |
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Agris Categories |
Animal husbandry
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AGROVOC TERMS |
Age.
Genotypes.
Glucocorticoids.
Immune response.
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Proposed Agrovoc |
Middle-Egypt rabbits;oxidative status;
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Publication Type |
Conference/Workshop
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