| Titles |
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English :
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preliminary attempts to prepare inactivated Babesia equi vaccine
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Arabic :
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محاولات مبدئية لتحضير لقاح البابيزيا اكواي المثبط
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| Abstract |
this study aimed to prepare and evaluate teh efficacy of Babesia equi inactivated vaccine for the prophylaxis against equine-babesios in Egypt. The lysate vaccine was prepared from infected erthrocytes, collected during the peak of parasitaemia. Three groups of equine were vaccinated wiht the different formulating vaccines (the first group recieved lysate vaccine alone, the second group inoculated with lysate vaccine formulated with Daea-dextran adjuvant while the third one vaccinated with lysate containing Quil-A adjuvant, a fourth group was kept as non vaccinated controls). the efficacy of the vaccine was evaluated in equines by the immunoflourescent assay (IFA) AND ENZYME LINKED IMMUNOSORBENT ASSAY (ELISA) tevhniques. all teh animals were challenged with virulent homologous B.equi strain 56 days post vaccination. The vaccinated horses were protected comparing with the non vaccinated controls which showed typpical signs of equine -babesiois (body temprature raised to 39.9oC and parasitaemia 7.5%). However, the B-equi lysate vaccine along with Dae-dextran adjuvant was the best to elicit a strong immune response against B-equi in experimental horses.
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| Publication year |
2008
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| Pages |
22-24
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| Organization Name |
Veterinary Serum and Vaccine Research Institute (VSVRI)
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| City |
المنوفية
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| serial title |
المؤتمر العلمي الخامس لكلية الطب البيطري بمدينة السادات
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| Author(s) from ARC |
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| Agris Categories |
Animal diseases
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| Publication Type |
Conference/Workshop
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