| Titles |
|
English :
|
The security hole of the immune system
|
|
| Abstract |
Just like any system, the immune system has a security hole. The process of maintaining tolerance to self antigens can be exploited by invaders to escape from an effective immune response, at least temporarily. In the presented work, the transport of antigens to the central organs of an immune system is identified as a critical issue for the induction of tolerance. As red blood cells (RBCs) are specialized for transport, work was directed towards studying the existence of fetal antigens in RBCs. When this was proved, the study of self and bacterial antigens in RBCs was conducted. The results point out that RBCs play a crucial role in tolerance and represent a security hole that is exploited positively by a fetus and negatively by microorganisms.
|
| Publication year |
2008
|
| Pages |
165-176
|
| Availability location |
ش السكة البيضاء - العباسية -القاهرة
|
| Availability number |
|
| Organization Name |
Veterinary Serum and Vaccine Research Institute (VSVRI)
|
| City |
cairo
|
| serial title |
Middle east and north africa conference for animal wealth
|
| Author(s) from ARC |
|
| External authors (outside ARC) |
محمود الرافعي
المعمل المركزي للرقابة على المستحضرات البيطرية
مرفت الأنصاري
كلية الطب البيطري - جامعة القاهرة
|
| Agris Categories |
Animal diseases
|
AGROVOC
TERMS |
Immunity.
|
| Publication Type |
Conference/Workshop
|