| Titles |
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English :
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Effect of Microbial Phytase Enzyme in Correction of Calcium,Phosphorus and biochemical Serum Constituents in Broilers Fed On Mycotoxicated or Mycotoxin Controlled Rations
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Arabic :
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تأثير انزيم الفيتاز الميكروبي في تصحيح الكالسيوم والفسفور والمحتويات البيوكيميائية المصلية في بدارى التسمين المغذاة على اعلاف تحتوي أو تم التحكم في السموم الفطرية بها.
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| Abstract |
In this study, 40 chicks of one day old, were vaccinated against Newcastle
and Gumboro diseases and fed standard ration uptill 21 days old, then, chicks
were divided into four groups each of them 10 chicks; 1st group received a
standard ration and kept as control group, 2nd group received a diet contaminated
with ochratoxin A 300 ppb, the 3rd group received a diet contaminated with
ochratoxin A 300 ppb + Hydrated sodium calcium aluminoselicate (HSCAS )
0.5% and the 4th group received a diet containing ochratoxin A 300ppb +
HSCAS 0.5% + phytase enzyme (500 FYT /gm) 24 g /100kg ration .This
feeding program continued for 2 weeks (uptill 35 days old ) . Blood and sera
samples were collected for hematological, biochemical and immunological
studies as well as organs (livers and kidneys)for histopathological studies. Bursal
weight was done for calculation of bursal index. Results showed disturbance in
both kidney and liver functions. Liver enzymes (GGT and AST) as well as uric
acid and creatinine showed significant increase and albumin showed significant
decrease. Chickens fed on ration contaminated With ochratoxin A showed
immunosuppresion which indicated by decreased globulin level, lymphopenia
and decreased antibody production. Normocytic hypochromic anemia was seen
in chicks treated by ochratoxin A. The addition of HSCAS to the ration lead to
disappearance of the toxic effect of ochratoxin A as shown in biochemical,
hematological and immunological results. The use of phytase enzymes in
combination with HSCAS in ochratoxin A contaminated feed restored the
normal values of serum Ca, P, proteins, albumin and globulin indicating the
importance of its use in ochratoxin A contaminated rations. Histopathological
studies showed the nephropathic effect of ochratoxin A as oedema of the
glomeruli and degeneration of the epithial lining of proximal and distal
convoluted tubules,while the liver tissue showed congestion and necrotic
changes of hepatocytes.
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| Publication year |
2002
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| Pages |
126-139
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| Availability location |
ش السكة البيضاء - العباسية -القاهرة
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| Availability number |
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| Organization Name |
Veterinary Serum and Vaccine Research Institute (VSVRI)
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| City |
القاهرة
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| serial title |
مجلة الباثولوجيا والباثولوجيا الإكلينيكية المقارنة
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| Author(s) from ARC |
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| External authors (outside ARC) |
عبد السلام احمد عبد السلام
معمل دمياط الفرعي-معمل المنصورة الفرعي - معهد بحوث صحة الحيوان
دعاء احمد حسين المطري
معمل دمياط الفرعي- معمل المنصورة الفرعي- معهد بحوث صحة الحيوان
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| Agris Categories |
Animal diseases
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AGROVOC
TERMS |
Calcium.
Enzymes.
Mycotoxins.
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| Publication Type |
Journal
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