Titles |
English :
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Laboratory studies on the effect of dicofol acaricide in adult male albino rats
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Arabic :
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دراسات معملية على تأثير دايكوفول- مبيداكاروس - فى ذكور الفئران البالغة.
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Abstract |
The acute, subacute and subchronic zoxicitities of dicofol, an organochlorine acaricied.Animals dosed PO subactely and subchronically with dicofol at high-and low-dose ( 4/1and 8/1 L.D) for 15 and 45 days respectively. The effects of dicofol exposure on some enzymatic activities,blood constutes and histopathological examination were investigated.Thyroxin (T4) was Significantly decreased, while, aspartate aminotransferase (AST) , alanine aminotransferase (ALT), cholesterol and creatinine sign increased in botal high-and low-does groups. moreover, similar increase in total protein (TP), albumin, uric acid was observed only in the high-does groups on the contrary, the low-dose group indicated a sign decrease.Concerning the thyroid gland, the acini were degenerated with periacinar hyperemic blood capillaries in acute cases associated with cysti dilatation with appearance of colloid in the acinar lumen. All these observation were associated with increase weight of liver, kidney and lungs and increase in mortalities.
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Publication year |
2003
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Pages |
234-220
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Availability location |
مكتبة معهد بحوث صحة الحيوان - شارع نادى الصيد - الدقى
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Availability number |
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Organization Name |
Animal Health Research Institute (AHRI)
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City |
القاهرة
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serial title |
مكتبة معهد بحوث صحة الحيوان
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Author(s) from ARC |
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Agris Categories |
Miscellaneous animal disordersVeterinary science and hygiene - General aspects
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AGROVOC TERMS |
Acaricides.
Araneae.
Dicofol.
Rats.
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Publication Type |
Journal
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