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Titles
English : Trials for the preparation of a lyophilized formalin inactivated foot and mouth disease vaccine and its application in guinea pigs in comparison with the liquid vaccine
Arabic : محاولات لتحضير لقاح الحمي القلاعية الفورمالين المجفد وتطبيقه في خنازير غينيا بالمقارنة باللقاح السائل
Abstract A lyophilized formalin- inactivated foot and mouth disease virus (FMOV) vaccine was prepared by the propagation of the virus on monolayer of BHK cells. Its titre was 109 TCID50/ml. and 0.5% gelatin has been chosen as a stabilizer for the freeze dried vaccine. Potency test in guinea pigs showed protection percentage of 100, 100, 50 and zero when using the liquid vaccine, undiluted to ¼, 1/16 and 1/64 respectively, while the percentages were 100, 88.89, 71.43, 33.34 and when using the dried vaccine undiluted, diluted to 1/4 , to 1/16, to 1/64 and to 1/256 respectively.
Publication year 1993
Pages 456-460
Availability location معهد بحوث الامصال واللقاحات البيطرية-ش السكة البيضاء-العباسية-القاهرة
Availability number
Organization Name
    Veterinary Serum and Vaccine Research Institute (VSVRI)
City القاهرة
serial title الجمعية الطبية المصرية
Author(s) from ARC
Agris Categories Animal diseases
AGROVOC
TERMS
Foot and mouth disease. Guinea pigs.
Proposed Agrovoc fmdv;lyophilized formalin;
Publication Type Journal

 
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