| Titles |
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English :
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Study on the immune responses of chickens vaccine with inactivated newcastle and egg drop syndrome in combination with pasteurella multocida lipopolysaccharide extract.
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Arabic :
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دراسات تأثير مستخلص الباستيريلا على الأستجابه المناعية للدواجن المحصنه بلقاحى النيوكاسل وظاهرة تدنى البيض .
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| Abstract |
This work was designed to study the effect of P.multocida lipopolysaccharide protein complex ( LPS ) on the immune response of chicken vaccinated with formalized oil adjuvant Newcastle (ND) and egg drop syndrome (EDS) . A total of 120 chickens were divided into 6 groups (20 chickens for each). The first three groups were vaccinated formalized oil adjuvant ND, EDS and LPS in single doses which are 0.5 ml, 0.5ml/ml I/M respectively. The fourth group was vaccinated with bivalent formalized oil adjuvant vaccine of NDV and EDS. The fifth group was vaccinated with bivalent formalized oil ND, EDS and LPS. The last two groups received 2 doses of LPS to study its mitogenic effect on the vaccinated chickens. Blood sera were collected weekly till 17 weeks for estimation of cell mediated immunity by lymphocyte transformation, phagocytic activity, phagocytic index and heterophils lymphocytes ratio. Humoral immunity was determined by IHA, HI, ELISA and challenge test. The obtaining data revealed that LPS protein complex of P.multocida had a mitogenic effect on chicken B lymphocytes vaccinated with combined NDV and EDS, enhancing the humoral antibodies and the protection against the challenge of P. multocida and NDV were 90%and 100% , respectively.
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| Publication year |
2004
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| Pages |
341-357
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| Availability location |
معهد بحوث الامصال واللقاحات البيطرية-- القاهرة - ش السكة البيضاء - العباسية ص ب 131
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| Availability number |
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| Organization Name |
Veterinary Serum and Vaccine Research Institute (VSVRI)
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| City |
زقازيق
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| serial title |
7th Sci, Vet. Med.Zag.Conf. المؤتمر العلمى السابع لكلية طب بيطرى ـ الزقازيق
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| Author(s) from ARC |
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| External authors (outside ARC) |
محمد عبد الغنى أبو الخير
معهد بحوث الأمصال واللقاحات البيطرية
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| Agris Categories |
Animal diseases
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AGROVOC
TERMS |
Chickens.
Egg drop syndrome.
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| Proposed Agrovoc |
Oil adjuvant Newcacastl;
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| Publication Type |
Conference/Workshop
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