| Titles |
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English :
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Specific and nonspecific immunization against Bovine Babesiosis in fattening calves using Babesia Bovis exoantigens and BCG
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Arabic :
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المناعة النوعية الغير نوعية ضد مرض البابيزيا في عجول التسمين باستخدام لقاح الأكسوأنتجين للبابيزيا بوفيز ولقاح BCG
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| Abstract |
Protective immunization of fattening calves against Babesia (B) bovis infection was investigated using cell culture exoantigens and/ or BCG vaccine. four groups, each consisted of 3 calves were used in this study. Group (1) was vaccinated with both B.bovis exoantigens and BCG vaccine while group (2)was vaccinated with B.bovis exoantigens and group (3) was vaccinated with BCG alone. Group (4) was left as a non vaccinated control. Specific anti B.bovis antibodies in serum of calves were detected using indirect immunoflurescent technique (IFAT). Hummeral immunity levels were detected in calves in griups (1&2) one week post vaccination and increased gradually. After the second dose of B.bovis exoantigens, the mean antibody titers continued to its peak at 6th week of vaccination(2.560 in group(1) and 1.706 in group(2).
The levels of protective immunity against B.bovis in different groups were assessed post challenge with 1x10-9 virulent B.bovis infected RBCs throught production of specific antibabesial (IFA titers), parasitaemia and elimination of parasite from blood after challenge and haematocrite value represented by reduction in packed cell volume (PCV).The best protective level was detected in group (1) then group (2). concerning to group(3), it's obvious that calves in this group were able to eliminate the parasite from blood post challenge while control group remained as carrier.
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| Publication year |
2006
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| Availability location |
مكتبة معهد بحوث الامصال و اللقاحات البيطرية
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| Availability number |
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| Organization Name |
Veterinary Serum and Vaccine Research Institute (VSVRI)
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| City |
الزقازيق
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| serial title |
المؤتمر الثامن لكلية الطب البيطري - الزقازيق بالغردقة8th Sc.Vet.Med.Zag Conference
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| Author(s) from ARC |
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| External authors (outside ARC) |
د.روماني منصور مكرم
معهد بحوث الأمصال واللقاحات البيطرية
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| Agris Categories |
Animal diseases
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AGROVOC
TERMS |
Babesia bovis.
Babesiosis.
Bovinae.
Calves.
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| Proposed Agrovoc |
اختبار التحدي المناعي;Haematocrite;
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| Publication Type |
Conference/Workshop
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