| Titles |
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English :
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Extraction of klebsiella pneumoniae capsular polysacharide and eavaluation of its adjuvanticity
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Arabic :
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استخلاص كبسول الكلبسيلا نيموني عديد السكريات وتقييم كفائته المناعية
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| Abstract |
Adjuvanticity and immunomodulating activity of crude capsular polysaccharide (CPS) prepared from Klebsiella pneumoniae treated with formaldehyde (CPS-K.1) and from untreated bacteria (CPS-K.2)was investigated in Guinea pigs immunized with freeze dried vaccine of inactivated or attenuated African Horse Sickness virus (AHSV) of serotype 9 as measured by assaying AHSV-neutralizing antibodies in their serum samples. The obtained results demonstrated that CPS-K.1 was highly effective in enhancing antibody response to inactivated AHSV;conversely, CPS-K2 induced an antibody unresponsiveness (immunological paralysis)to inactivated AHSV, and a marked depressed antibody response to attenuated AHSV in immunized Guinea pigs.
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| Publication year |
2000
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| Availability location |
مكتبة معهد بحوث الامصال و اللقاحات البيطرية
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| Availability number |
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| Organization Name |
Veterinary Serum and Vaccine Research Institute (VSVRI)
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| City |
اسيوط
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| serial title |
المجلة الطبية البيطرية باسيوط Assiut. Vet. Med.J
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| Author(s) from ARC |
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| External authors (outside ARC) |
د/منصور هاشم عبد الباقي
المعمل المركزي للرقابة على المستحضرات البيطرية-العباسية
د.رأفت عزمي ديمتري
معهد بحوث الأمصال واللقاحات البيطرية
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| Agris Categories |
Animal diseases
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AGROVOC
TERMS |
Guinea pigs.
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| Proposed Agrovoc |
kLEBSIELLA Pnuemoniae;طاعون الخيل الفيروسي الميت;
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| Publication Type |
Journal
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